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Ted Kandell

MINOR ALLELE PROGRAM REPORT
===========================

Ted Kandell        ('tk')  '284'     23andMe Results        Chromosomes 1-22, X       Revised 17 June 2013


The program finds just under 60 'rare/uncommon' SNPs from the 900,000+ tested by 23andMe.

There are no 'homozygous-recessive' results; and no suggestion of consanguinity.

The most interesting result is perhaps for:

'AT'	rs1801155	APC  adenomatous polyposis coli		- missense I1307K

which is a 'carrier' status for a form of "Jewish" colon cancer'.

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mtDNA Haplogroup HV5

263G 750G 1438G 2706G 3397G 4769G 7028T 8860G 13105G 15326G 

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RESULTS
=======
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rs3001722	 at Chr1a:43769007	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00731
rs12751479	 at Chr1b:97828595	 gave 'GT'  The minor allele is 'T' with a MAF = 0.00228
rs2275237	 at Chr1b:149052435	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00000.
rs16846879	 at Chr1c:198789118	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00548
rs16847867	 at Chr1c:222636859	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00000

rs11125073	 at Chr2a:46468251	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00411
rs2370192	 at Chr2b:137343454	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00731
rs2599		 at Chr2c:198125481	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00400.
rs13006003	 at Chr2c:203562831	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs41272687	 at Chr2c:219387121	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00685

rs34421970	 at Chr3a:33034985	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00594
rs2176898	 at Chr3b:108030375	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00731.
rs12721602	 at Chr3b:120982546	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00776


rs17488750	 at Chr4a:16139889	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00868
rs11936089	 at Chr4a:17620962	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00000

rs1801155	 at Chr5b:112203110	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00100
rs34353925	 at Chr5c:146529671	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00365
rs8192451	 at Chr5c:148188207	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00137
rs62642053	 at Chr5c:178354533	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00999

rs16870475	 at Chr6a:10662308	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00000
rs58554303	 at Chr6a:28607546	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00868
rs17200768	 at Chr6a:31661914	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00502
rs3101943	 at Chr6a:33016730	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00594
rs9658089	 at Chr6a:35453137	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00137
rs12189820	 at Chr6b:132910800	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00548

rs35703484	 at Chr7a:17303122	 gave 'AC'  The minor allele is 'A' with a MAF = 0.00959
rs10253202	 at Chr7a:17304950	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00950
rs2158061	 at Chr7a:24802007	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00914
rs28371763	 at Chr7b:99192744	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00685
rs7801492	 at Chr7b:100030053	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs11765270	 at Chr7b:103454826	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00868
rs10487818	 at Chr7b:105697297	 gave 'AT'  The minor allele is 'T' with a MAF = 0.00639

rs268		 at Chr8a:19857809	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00400
rs9692790	 at Chr8a:29721425	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00457

rs10811464	 at Chr9a:21066087	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00182
rs9282543	 at Chr9b:106639197	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00045.
rs17418918	 at Chr9b:131613259	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00731

rs12413425	 at Chr10a:44871820	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00731
rs4933986	 at Chr10b:85983816	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs36078476	 at Chr10b:103815919	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00411.
rs4918857	 at Chr10b:115339452	 gave 'AT'  The minor allele is 'T' with a MAF = 0.00274

rs4647760	 at Chr11a:47217127	 gave 'AC'  The minor allele is 'A' with a MAF = 0.00594
rs11227700	 at Chr11a:66655756	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00457
rs3212861	 at Chr11a:69164632	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs10894684	 at Chr11b:132849346	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00868

rs17725914	 at Chr12a:6501249	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00900
rs33995883	 at Chr12a:39026953	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00914
rs5745068	 at Chr12b:131712813	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00457.

rs12184642	 at Chr13b:76637306	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00685
rs7325797	 at Chr13b:92132507	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00959

rs11568438	 at Chr14:22352176	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00776.
rs2230500	 at Chr14:60993992	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00600
rs61329727	 at Chr14:69322681	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00200

rs721151	 at Chr15:63850614	 gave 'AC'  The minor allele is 'A' with a MAF = 0.00822.

rs17227438	 at Chr16:88331856	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00091.

17-

rs1573346	 at Chr18:22798669	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00502.

rs59796499	 at Chr19:5795547	 gave 'GT'  The minor allele is 'T' with a MAF = 0.00137

20-
21-

rs4253791	 at Chr22:44964591	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00639

rs17842890	 at ChrX:2487187	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00999
rs11797182	 at ChrX:102207587	 gave 'G'  The minor allele is 'G' with a MAF = 0.00999
rs7880514	 at ChrX:133983478	 gave 'C'  The minor allele is 'C' with a MAF = 0.00904
rs11465836	 at ChrX:152935534	 gave 'T'  The minor allele is 'T' with a MAF = 0.00421.


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MISSENSE LIST
=============
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rs2275237	 at Chr1b:149052435	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00000.
rs2275237	ARNT  aryl hydrocarbon receptor nuclear translocator				- missense P691L
('tk')		'AG' MAF = 0.00000. Possibly 2% in Asia and absent elsewhere.
		The change P<>L is fairly common and unlikely to be significant.
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rs41272687	 at Chr2c:219387121	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00685
rs41272687	CYP27A1  cytochrome P450, family 27, subfamily A, polypeptide 1			- missense P384L
('ss')		'CT' MAF = 0.00685 Appears 3% worldwide, highest in Europe.
		The change P<>L is fairly common,  and unlikely to be significant.
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rs34421970	 at Chr3a:33034985	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00594
rs34421970	GLB1  galactosidase, beta 1							- missense L305F
('ma')		'AG' MAF = 0.00594 Possibly 2% worldwide.
		The change L<>F is common and unlikely to be significant.
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rs1801155	 at Chr5b:112203110	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00100
rs1801155	APC  adenomatous polyposis coli							- missense I1307K
('tk')		'AT' MAF = 0.00100 Uncommon, appears 1 per 1000.
		The change I<>K is uncommon and the homozygous form could be significant.
		Carrier for 'Jewish' colon cancer risk, see:
		http://www.ncbi.nlm.nih.gov/pubmed/16228836, http://www.ncbi.nlm.nih.gov/pubmed/14624392
		& http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889843/pdf/1471-2156-11-39.pdf
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rs62642053	 at Chr5c:178354533	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00999
rs62642053	GRM6  glutamate receptor, metabotropic 6					- missense A7T
('tk')		'CT' MAF = 0.00999 Possibly 1% in Europe.
		The change A<>T is common and unlikely to be significant.
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rs58554303	 at Chr6a:28607546	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00868
rs58554303	GPX5  glutathione peroxidase 5 (epididymal androgen-related protein)		- missense L85P
('tk')		'CT' MAF = 0.00868 Possibly 3% in Europe.
		The change L<>P is fairly common and unlikely to be significant.
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rs7801492	 at Chr7b:100030053	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs7801492	FBXO24  F-box protein 24							- missense R302H
('tk')		'AG' MAF = 0.00685 Appears 4% in Europe, 2% in Asia and absent from Africa.
		The change R<>H is uncommon and the homozygous form could be significant.
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rs268		 at Chr8a:19857809	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00400
rs268		LPL  lipoprotein lipase								- missense N318S
('bb')		'AG' MAF = 0.00400 Possibly 1-2% in europe and absent elsewhere.
		The change N<>S is fairly common and is unlikely to be significant.
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rs9282543	 at Chr9b:106639197	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00045.
rs9282543	ABCA1  ATP-binding cassette, sub-family A (ABC1), member 1			- missense V399A
('tk')		'AG' MAF = 0.00045. Appears 1% in Europe and absent elsewhere.
		The change V<>A is common and unlikely to be significant.
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rs36078476	 at Chr10b:103815919	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00411.
rs36078476	HPS6  Hermansky-Pudlak syndrome 6						- missense L233R
('ss')		'GT' MAF = 0.00411. Appears 1% worldwide.
		The change L<>R is uncommon and the homozygous form could be significant.
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rs4918857	 at Chr10b:115339452	 gave 'AT'  The minor allele is 'T' with a MAF = 0.00274
rs4918857	NRAP  nebulin-related anchoring protein						- missense L1684Q
('cm')		'AT' MAF = 0.00274 Appears about 1% worldwide, highest in Europe.
		The change L<>Q is fairly uncommon and the homozygous form could be significant.
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rs17725914	 at Chr12a:6501249	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00900
rs17725914	NCAPD2  non-SMC condensin I complex, subunit D2					- missense K580R
('mh') 		'AG' MAF = 0.00900 Maybe 1-2% in Europe, and absent elsewhere.
		The change K<>R is uncommon and could be significant. An SNP to watch.
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rs33995883	 at Chr12a:39026953	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00914
rs33995883	LRRK2  leucine-rich repeat kinase 2						- missense N2081D
('tk')		'AG' MAF = 0.00914 Appears about 2% worldwide.
		The change N<>D is common and unlikely to be significant.
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rs5745068	 at Chr12b:131712813	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00457.
rs5745068	POLE  polymerase (DNA directed), epsilon					- missense R2165H
('tk')		'CT' MAF = 0.00457. Appears about 1% worldwide.
		The R<>H is uncommon and the homozygous form could be significant.
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rs11568438	 at Chr14:22352176	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00776.
rs11568438	SLC7A7  solute carrier family 7							- missense A91V
('ma')		'AG' MAF = 0.00776. Appears 4% in Europe, 2% in Asia and absent from Africa.
		The change A<>V is common and unlikely to be significant.
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rs2230500	 at Chr14:60993992	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00600
rs2230500	PRKCH  protein kinase C, eta							- missense V374I
('a')		'AG' MAF = 0.00600 Worldwide 1%, but 2-3% Asia and absent elsewhere.
		The change V<>I is very common, and normally harmless.
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rs59796499	 at Chr19:5795547	 gave 'GT'  The minor allele is 'T' with a MAF = 0.00137
rs59796499	FUT3  fucosyltransferase 3 (Lewis blood group)					- missense Q102K
('tk')		'GT' MAF = 0.00137 Possibly 4 per 1000 worldwide.
		The change Q<>K is uncommon and the homozygous form could be significant.

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FULL SUMMARY
============
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rs3001722	 at Chr1a:43769007	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00731
rs3001722	Intergenic									-
('ls')		'AT' MAF = 0.00731 Possibly about 2% in Europe.
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rs12751479	 at Chr1b:97828595	 gave 'GT'  The minor allele is 'T' with a MAF = 0.00228
rs12751479	DPYD  dihydropyrimidine dehydrogenase						- intron
('jw')		'GT' MAF = 0.00228 Appears 1% in Europe and absent elsewhere.
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rs2275237	 at Chr1b:149052435	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00000.
rs2275237	ARNT  aryl hydrocarbon receptor nuclear translocator				- missense P691L
('tk')		'AG' MAF = 0.00000. Possibly 2% in Asia and absent elsewhere.
		The change P<>L is fairly common and unlikely to be significant.
----------------------------------------------------------------------------------------------------------------
rs16846879	 at Chr1c:198789118	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00548
rs16846879	KIF14  kinesin family member 14							- UTR-3
('tk')		'AG' MAF = 0.00548 Possibly 4% in Africa and absent elsewhere.
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rs16847867	 at Chr1c:222636859	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00000
rs16847867	Intergenic									-
('cm')		'AG' MAF = 0.00000 Appears up to 40% in Africa, absent elsewhere.
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rs11125073	 at Chr2a:46468251	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00411
rs11125073	Intergenic									-
('tk')		'CT' MAF = 0.00411 Appears 3% in Europe and absent elsewhere.
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rs2370192	 at Chr2b:137343454	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00731
rs2370192	Intergenic									-
('si')		'AT' MAF = 0.00731 Possibly up to 8% in Europe.
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rs2599		 at Chr2c:198125481	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00400.
rs2599		MOB4  MOB family member 4, phocein						- UTR-3
('lw')		'CT' MAF = 0.00400. The 1000 Genome Project gives 4 per 1000.
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rs13006003	 at Chr2c:203562831	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs13006003	Intergenic									-
('f0')		'AG' MAF = 0.00685 Possibly 5% in Europe and less elsewhere.
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rs41272687	 at Chr2c:219387121	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00685
rs41272687	CYP27A1  cytochrome P450, family 27, subfamily A, polypeptide 1			- missense P384L
('ss')		'CT' MAF = 0.00685 Appears 3% worldwide, highest in Europe.
		The change P<>L is fairly common,  and unlikely to be significant.
----------------------------------------------------------------------------------------------------------------
rs34421970	 at Chr3a:33034985	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00594
rs34421970	GLB1  galactosidase, beta 1							- missense L305F
('ma')		'AG' MAF = 0.00594 Possibly 2% worldwide.
		The change L<>F is common and unlikely to be significant.
----------------------------------------------------------------------------------------------------------------
rs2176898	 at Chr3b:108030375	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00731.
rs2176898	Intergenic									-
('kr')		'GT' MAF = 0.00731. Appears 3% in Europe and less elsewhere.
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rs12721602	 at Chr3b:120982546	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00776
rs12721602	NR1I2  nuclear receptor subfamily 1, group I, member 2				- UTR-5
('eb')		'AG' MAF = 0.00776 Possibly 8% in Europe and absent elsewhere.
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rs17488750	 at Chr4a:16139889	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00868
rs17488750	LDB2  LIM domain binding 2							- intron
('cb')		'CT' MAF = 0.00868 Appears 7% in Europe and less elsewhere.
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rs11936089	 at Chr4a:17620962	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00000
rs11936089	LCORL  ligand dependent nuclear receptor corepressor-like			- intron
('ss')		'CT' MAF = 0.00000 Appears rare in Europe & Asia. Possibly 3% in Africa
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rs1801155	 at Chr5b:112203110	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00100
rs1801155	APC  adenomatous polyposis coli							- missense I1307K
('tk')		'AT' MAF = 0.00100 Uncommon, appears 1 per 1000.
		The change I<>K is uncommon and the homozygous form could be significant.
		Carrier for 'Jewish' colon cancer risk, see:
		http://www.ncbi.nlm.nih.gov/pubmed/16228836, http://www.ncbi.nlm.nih.gov/pubmed/14624392
		& http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2889843/pdf/1471-2156-11-39.pdf
----------------------------------------------------------------------------------------------------------------
rs34353925	 at Chr5c:146529671	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00365
rs34353925	Intergenic									-
('ab')		'CT' MAF = 0.00365 The 1000 genome Project gives 3 per 1000.
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rs8192451	 at Chr5c:148188207	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00137
rs8192451	ADRB2  adrenergic, beta-2-, receptor, surface					- UTR-3
('ss')		'CT' MAF = 0.00137 Maybe about 1% worldwide.
----------------------------------------------------------------------------------------------------------------
rs62642053	 at Chr5c:178354533	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00999
rs62642053	GRM6  glutamate receptor, metabotropic 6					- missense A7T
('tk')		'CT' MAF = 0.00999 Possibly 1% in Europe.
		The change A<>T is common and unlikely to be significant.
----------------------------------------------------------------------------------------------------------------
rs16870475	 at Chr6a:10662308	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00000
rs16870475	GCNT2  glucosaminyl (N-acetyl) transferase 2, (I blood group)			- intron
('tk')		'AG' MAF = 0.00000 Possibly 20% in Africa, and absent elsewhere.
----------------------------------------------------------------------------------------------------------------
rs58554303	 at Chr6a:28607546	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00868
rs58554303	GPX5  glutathione peroxidase 5 (epididymal androgen-related protein)		- missense L85P
('tk')		'CT' MAF = 0.00868 Possibly 3% in Europe.
		The change L<>P is fairly common and unlikely to be significant.
----------------------------------------------------------------------------------------------------------------
rs17200768	 at Chr6a:31661914	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00502
rs17200768	LST1  leukocyte specific transcript 1						- nearGene-5
('tk')		'CT' MAF = 0.00502 Possibly 3% in Europe.
----------------------------------------------------------------------------------------------------------------
rs3101943	 at Chr6a:33016730	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00594
rs3101943	HLA-DMB  major histocompatibility complex, class II, DM beta			- UTR-5
('tk')		'AG' MAF = 0.00594 Appears 2% in Europe and absent elsewhere.
----------------------------------------------------------------------------------------------------------------
rs9658089	 at Chr6a:35453137	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00137
rs9658089	PPARD  peroxisome proliferator-activated receptor delta				- intron
('tk')		'CT' MAF = 0.00137 Possibly 2% worldwide.
----------------------------------------------------------------------------------------------------------------
rs12189820	 at Chr6b:132910800	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00548
rs12189820	Intergenic									-
('tk')		'CT' MAF = 0.00548 Appears 5% in Europe and absent elsewhere.
----------------------------------------------------------------------------------------------------------------
rs35703484	 at Chr7a:17303122	 gave 'AC'  The minor allele is 'A' with a MAF = 0.00959
rs35703484	AHR  aryl hydrocarbon receptor							- nearGene-5
('tk')		'AC' MAF = 0.00959 Possibly 1% in Europe.
----------------------------------------------------------------------------------------------------------------
rs10253202	 at Chr7a:17304950	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00950
rs10253202	AHR  aryl hydrocarbon receptor							 - UTR-5
('tk')		'AG' MAF = 0.00950 Possibly 3% in Europe.
----------------------------------------------------------------------------------------------------------------
rs2158061	 at Chr7a:24802007	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00914
rs2158061	Intergenic									-
('mj')		'AG' MAF = 0.00914 Appears about 1% in Europe and Africa, absent in Asia.
----------------------------------------------------------------------------------------------------------------
rs28371763	 at Chr7b:99192744	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00685
rs28371763	CYP3A4  cytochrome P450, family 3, subfamily A, polypeptide 4			- UTR-3
		'AT' MAF = 0.00685 Possibly 13% in Europe and much less elsewhere.
----------------------------------------------------------------------------------------------------------------
rs7801492	 at Chr7b:100030053	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs7801492	FBXO24  F-box protein 24							- missense R302H
('tk')		'AG' MAF = 0.00685 Appears 4% in Europe, 2% in Asia and absent from Africa.
		The change R<>H is uncommon and the homozygous form could be significant.
----------------------------------------------------------------------------------------------------------------
rs11765270	 at Chr7b:103454826	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00868
rs11765270	Intergenic									-
('tk')		'AG' MAF = 0.00868 Possibly 10% in Europe, 1% in Africa and absent from Asia.
----------------------------------------------------------------------------------------------------------------
rs10487818	 at Chr7b:105697297	 gave 'AT'  The minor allele is 'T' with a MAF = 0.00639
rs10487818	NAMPT  nicotinamide phosphoribosyltransferase					- intron
('lw')		'AT' MAF = 0.00639 Appears 8% in Europe and absent elsewhere.
----------------------------------------------------------------------------------------------------------------
rs268		 at Chr8a:19857809	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00400
rs268		LPL  lipoprotein lipase								- missense N318S
('bb')		'AG' MAF = 0.00400 Possibly 1-2% in europe and absent elsewhere.
		The change N<>S is fairly common and is unlikely to be significant.
----------------------------------------------------------------------------------------------------------------
rs9692790	 at Chr8a:29721425	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00457
rs9692790	Intergenic									-
('ss')		'CT' MAF = 0.00457 The 1000 Genome Project gives 6 per 1000.
----------------------------------------------------------------------------------------------------------------
rs10811464	 at Chr9a:21066087	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00182
rs10811464	Intergenic									-
('ut')		'AG' MAF = 0.00182 Appears 1% in Europe and absent elsewhere.
----------------------------------------------------------------------------------------------------------------
rs9282543	 at Chr9b:106639197	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00045.
rs9282543	ABCA1  ATP-binding cassette, sub-family A (ABC1), member 1			- missense V399A
('tk')		'AG' MAF = 0.00045. Appears 1% in Europe and absent elsewhere.
		The change V<>A is common and unlikely to be significant.
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rs17418918	 at Chr9b:131613259	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00731
rs17418918	TOR1B  torsin family 1, member B (torsin B)					- UTR-3
('ut')		'GT' MAF = 0.00731 Poor population data.
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rs12413425	 at Chr10a:44871820	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00731
rs12413425	Intergenic									-
('wv')		'GT' MAF = 0.00731 Appears 1% in Europe and absent elsewhere.
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rs4933986	 at Chr10b:85983816	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs4933986	LRIT1  leucine-rich repeat, immunoglobulin-like and transmembrane domains 1	- synonymous N296N
('rr')		'AG' MAF = 0.00685 Possibly 10% in Europe, 2% in Asia and absent from Africa.
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rs36078476	 at Chr10b:103815919	 gave 'GT'  The minor allele is 'G' with a MAF = 0.00411.
rs36078476	HPS6  Hermansky-Pudlak syndrome 6						- missense L233R
('ss')		'GT' MAF = 0.00411. Appears 1% worldwide.
		The change L<>R is uncommon and the homozygous form could be significant.
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rs4918857	 at Chr10b:115339452	 gave 'AT'  The minor allele is 'T' with a MAF = 0.00274
rs4918857	NRAP  nebulin-related anchoring protein						- missense L1684Q
('cm')		'AT' MAF = 0.00274 Appears about 1% worldwide, highest in Europe.
		The change L<>Q is fairly uncommon and the homozygous form could be significant.
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rs4647760	 at Chr11a:47217127	 gave 'AC'  The minor allele is 'A' with a MAF = 0.00594
rs4647760	DDB2  damage-specific DNA binding protein 2					- UTR-3
('bb')		'AC' MAF = 0.00594 Possibly 4% in Europe and absent elsewhere.
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rs11227700	 at Chr11a:66655756	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00457
rs11227700	KDM2A  lysine (K)-specific demethylase 2A					- intron
('pa')		'AG' MAF = 0.00457 Maybe 3% in Europe and absent elsewhere.
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rs3212861	 at Chr11a:69164632	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00685
rs3212861	CCND1  cyclin D1								- nearGene-5
('k')		'AG' MAF = 0.00685 Worldwide 2-3%, maybe up to 5% in Italy.
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rs10894684	 at Chr11b:132849346	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00868
rs10894684	OPCML  opioid binding protein/cell adhesion molecule-like			- intron
('gr')		'AG' MAF = 0.00868 Appears 7% in Europe and less elsewhere.
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rs17725914	 at Chr12a:6501249	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00900
rs17725914	NCAPD2  non-SMC condensin I complex, subunit D2					- missense K580R
('mh') 		'AG' MAF = 0.00900 Appears 1% in Europe, and absent elsewhere.
		The change K<>R is uncommon and  the homozygous form could be significant.
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rs33995883	 at Chr12a:39026953	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00914
rs33995883	LRRK2  leucine-rich repeat kinase 2						- missense N2081D
('tk')		'AG' MAF = 0.00914 Appears about 2% worldwide.
		The change N<>D is common and unlikely to be significant.
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rs5745068	 at Chr12b:131712813	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00457.
rs5745068	POLE  polymerase (DNA directed), epsilon					- missense R2165H
('tk')		'CT' MAF = 0.00457. Appears about 1% worldwide.
		The R<>H is uncommon and the homozygous form could be significant.
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rs12184642	 at Chr13b:76637306	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00685
rs12184642	MYCBP2  MYC binding protein 2							- intron
('mh')		'CT' MAF = 0.00685 Poor data. Maybe 5% in Europe, so lower elsewhere.
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rs7325797	 at Chr13b:92132507	 gave 'CT'  The minor allele is 'C' with a MAF = 0.00959
rs7325797	GPC5  glypican 5								- intron
('tk')		'CT' MAF = 0.00959 Appears 6% in Africa and absent elsewhere.
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rs11568438	 at Chr14:22352176	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00776.
rs11568438	SLC7A7  solute carrier family 7							- missense A91V
('ma')		'AG' MAF = 0.00776. Appears 4% in Europe, 2% in Asia and absent from Africa.
		The change A<>V is common and unlikely to be significant.
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rs2230500	 at Chr14:60993992	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00600
rs2230500	PRKCH  protein kinase C, eta							- missense V374I
('a')		'AG' MAF = 0.00600 Worldwide 1%, but 2-3% Asia and absent elsewhere.
		The change V<>I is very common, and normally harmless.
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rs61329727	 at Chr14:69322681	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00200
rs61329727	SLC10A1  solute carrier family 10						- synonymous K151K
('tk')		'CT' MAF = 0.00200 Possibly 4 per 1000 worldwide.
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rs721151	 at Chr15:63850614	 gave 'AC'  The minor allele is 'A' with a MAF = 0.00822.
rs721151	DENND4A  DENN/MADD domain containing 4A						- intron
('lr')		'AC' MAF = 0.00822. Appears 1% in Europe.
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rs17227438	 at Chr16:88331856	 gave 'AG'  The minor allele is 'A' with a MAF = 0.00091.
rs17227438	FANCA  Fanconi anemia, complementation group A				- UTR-3
('tk')		'AG' MAF = 0.00091. An uncommon SNP.
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rs1573346	 at Chr18:22798669	 gave 'CT'  The minor allele is 'T' with a MAF = 0.00502.
rs1573346	CHST9  carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9		- intron
('gn')		'CT' MAF = 0.00502. Appears about 3% in Europe and 1% in Africa.
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rs59796499	 at Chr19:5795547	 gave 'GT'  The minor allele is 'T' with a MAF = 0.00137
rs59796499	FUT3  fucosyltransferase 3 (Lewis blood group)					- missense Q102K
('tk')		'GT' MAF = 0.00137 Possibly 4 per 1000 worldwide.
		The change Q<>K is uncommon and the homozygous form could be significant.
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rs4253791	 at Chr22:44964591	 gave 'AT'  The minor allele is 'A' with a MAF = 0.00639
rs4253791	PPARA  peroxisome proliferator-activated receptor alpha				- intron
('tk')		'AT' MAF = 0.00639 Appears 4% in Europe and absent elsewhere.
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rs17842890	 at ChrX:2487187	 gave 'AG'  The minor allele is 'G' with a MAF = 0.00999
rs17842890	Intergenic									-
		'AG' MAF = 0.00999 Possibly 4% in Europe.
('sy')		'GG'
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rs11797182	 at ChrX:102207587	 gave 'G'  The minor allele is 'G' with a MAF = 0.00999
rs11797182	BEX1  brain expressed, X-linked 1						- nearGene-5
('k')		'AG' MAF = 0.00999 Possibly 2% in Europe and less elsewhere.
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rs7880514	 at ChrX:133983478	 gave 'C'  The minor allele is 'C' with a MAF = 0.00904
rs7880514	FAM127C  family with sequence similarity 127, member C				- UTR-3
('tk'-XY)		'C' MAF = 0.00904 An uncommon SNP.
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rs11465836	 at ChrX:152935534	 gave 'T'  The minor allele is 'T' with a MAF = 0.00421.
rs11465836	IRAK1  interleukin-1 receptor-associated kinase 1				- intron
('k')		'GT' MAF = 0.00421. Appears about 1% worldwide.


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